Others, such as confusion, high blood pressure or a drop in potassium, can occur on a shorter time frame. The most serious prednisone side effects that may happen within a week or two of use are dangerous blood clots (deep vein thrombosis), ulcers and infections. Typical starting dosage: This may vary from 5 mg to 60 mg per day taken once per day, depending on the condition being treated. For immediate-release tablets only: To reduce side effects, twice. About Side effects of prednisone taken for 5 days. Workers fixed the hole, replaced carpet, repainted the entire unit and redid one and a half walls of drywall, according to apartment records. Learn More This steroid medication reduces inflammation and is used to treat many conditions, such as allergies, asthma and certain types of arthritis. Prednisolone 5 mg is a low-dose steroid, but side effects can still happen 2. Short-term effects may occur within a few days. Long-term effects typically do not develop unless you've been taking prednisolone for several months 2. Yes, she prescribed 50mg for 5 days, 1 tablet each day. I have not taken the tablet today because of all the side effects I am getting (rapid heart beat, muscle pain etc), so today did not take it (overall took 2 tablets). 3 are left. The body itself produces a substance that is equivalent to about 5 mg of prednisone. A short course of 10 mg of prednisone a day may not cause side effects. However, either a dosage of 10 to 20 mg a day for a month or more—or a dosage of more than 20 mg a day for any length of time—could cause some adverse effects.   Prednisone is a wonderful drug in that it does the job it's designed to do. However, there can be some very unpleasant side effects associated with it. Seems the most noticeable and common are insomnia and increased appetite. A 5 day course is very short but even on that I would see side effects when I take it. The golden rule with Prednisone. PrednISONE is a very strong steroid. I had chest congestion, feeling weak and lost appetite the day after my last dosage. I would suggest you calling your pharmacy and talk to a pharmacist regarding to your side effects. I received very helpful advices and instructions from my pharmacist. In deed the pharmacist know medicines far more better than family doctors. Hope you feel better. Prednisone is a prescription medication used most commonly to treat a variety of common diseases and conditions. Learn about side effects, drug interactions, dosages, warnings, and more.